22nd May 2025

A 25-year-old patient presents to your general practice complaining of erectile dysfunction, fatigue, gynecomastia and weight gain.

A 25-year-old patient presents to your general practice complaining of erectile dysfunction, fatigue, gynecomastia and weight gain. After further questioning, he reveals that he feels very cold when walking outside, even though it is summer. Furthermore, his gloves and shoes no longer fit and he has been walking into the side of door frames and walls. On physical examination, his penis and testis show no significant abnormalities. You decide to perform laboratory investigations on this patient; what is the likely pattern from the laboratory investigations given this patient’s presentation? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.