23rd May 2025

A 38-year-old female presents to GP with complaints of weight gain, arthritic pain in her joints, excessive sweating, deepening to her voice and widening of her hands and feet for the last 5 years.

A 38-year-old female presents to GP with complaints of weight gain, arthritic pain in her joints, excessive sweating, deepening to her voice and widening of her hands and feet for the last 5 years. Her husband complains she snores. More recently, she has developed an intermittent headache. Her only past medical history is a hysterectomy 8 years previously. 

What are the most appropriate investigations to diagnose the likely pathology?

Select the SINGLE most appropriate option from the list below. Select ONE option only.