25th May 2025

A 26-year-old female with cystic fibrosis is seen in the genetics clinic for pre-natal counselling.

A 26-year-old female with cystic fibrosis is seen in the genetics clinic for pre-natal counselling. Her husband does not have any clinical symptoms suggestive of CF and does not have any family history of CF. He has not undergone any genetic screening tests.

Assuming the carrier rate of the CF mutation within the community is 1/25, what are the chances that her children would be affected?

Select the SINGLE most appropriate option from the list below. Select ONE option only.