25th May 2025

Rare Functional Neuroendocrine tumours

Discussed below are some functional pancreatic neuroendocrine tumours. These can occur on their own or in around 10% as part of a familial endocrine tumour group like MEN or VHL. Therefore, family history is important here. Neuroendocrine tumours can also be non-functional, when they do not secrete an enzyme but can still be locally invasive and metastasise.