A 19-year-old male patient comes into A&E with a fever and headache, which has now progressed to fluctuating confusion, amnesia, unusual behaviour, and multiple seizures. | Medibuddy
28th May 2025

A 19-year-old male patient comes into A&E with a fever and headache, which has now progressed to fluctuating confusion, amnesia, unusual behaviour, and multiple seizures.

A 19-year-old male patient comes into A&E with a fever and headache, which has now progressed to fluctuating confusion, amnesia, unusual behaviour, and multiple seizures.

A CT head was done initially. This was followed by an MRI head which showed:

Epilepsy

The CSF findings are:

Finding Result Reference Ranges
WCC 120 cells/ µL 0 – 5 cells/µL
Cell differential Lymphocytic pleocytosis —
RBC 400 cells/mm3 0-10 cells/mm3
Protein 0.21 g/L 0.15 – 0.45 g/L
Glucose 2.3 mmol/L 2.8 – 4.2 mmol/L

Of the options below, which is the most likely infectious cause of epilepsy in this case?

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