4th June 2025

Complications

Primary cutaneous follicle centre lymphoma:

• Close to 95% of patients are alive at 5 years post-diagnosis.
• Disease recurs in >45% patients.
• In 5 – 10% patients, PCFCL will metastasise to extracutaneous sites.

Primary cutaneous marginal zone B-cell lymphoma:

• Up to 99% of patients are alive at 5 years post-diagnosis.
• Metastasis is rare
• PCMZBCL may transform into systemic diffuse large B-cell lymphoma, but this is very rare

Primary cutaneous diffuse large B-cell lymphoma, leg-type:

• Nearly ≥60% of patients relapse after treatment
• In 30% the disease will spread to extracutaneous sites.