5th June 2025

A 60-year-old male develops reticular mottling of the skin on his legs.

A 60-year-old male develops reticular mottling of the skin on his legs. He has also noticed flat scaly patches developing on his arms since he has started wearing short-sleeved tops. He suffers from hypertension and benign prostatic hyperplasia. A urine dip reveals presence of protein and blood tests show a positive ANA. He is diagnosed with SLE.

Which of the below is NOT a known genetic risk factor for SLE?

Select the SINGLE most appropriate option from the list below. Select ONE option only.