9th June 2025

Gardner’s syndrome

Gardner’s syndrome is a condition of autosomal dominant inheritance. The condition has similar genetic variations on the adenomatous polyposis coli (APC) gene as seen in Familial Adenomatous Polyposis (FAP) and both are associated with an increased colorectal cancer risk.

Clinical features

Colon polyps
Osteomas
Epidermoid or sebaceous cysts
Desmoid tumours

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