9th June 2025

Neurofibromatosis Type 2 (NF2)

This is less common than NF1. Its inheritance pattern is also autosomal dominant. Tumours typically arise on the Schwann cells. 

Clinical Features 

Neural tumours tend to arise with patients presenting with bilateral hearing loss and balance issues:

• Acoustic neuromas (bilateral)
• Meningiomas 
• Cutaneous neurofibromas

Image Source: Wikimedia Commons (2021). Neurofibroma in Neurofibromatosis, Licensed under a creative commons licence. Available for free at: https://commons.wikimedia.org/wiki/File:Neurofibroma_in_neurofibromatosis_type_1.png (Accessed 23 May 2025).