17th August 2020

A 36-year-old woman presents for an ultrasound scan at 11 weeks gestation

A 36-year-old woman presents for an NHS ultrasound scan at 11 weeks gestation. This is her first pregnancy, and so far, it has been uncomplicated. On the ultrasound, the nuchal translucency is 4 mm. Her blood test results show a low PAPP-A. She is informed there is a high likelihood that the foetus may have trisomy 21 (≥ 1 in 150).

Which is the next most appropriate investigation?

Select the SINGLE most appropriate option from the list below. Select ONE option only.