6th July 2026

A 35-year-old woman attends hospital with swelling, tenderness, and pitting oedema of her left leg.

A 35-year-old woman attends hospital with swelling, tenderness, and pitting oedema of her left leg. She had initially put the symptoms down to a running injury, but they have worsened despite following advice from her GP to rest the leg. Her D-dimer is raised, and venous ultrasound confirms a DVT. Her renal and liver function are both normal. Her only past medical history is childhood asthma, and she is on the oral contraceptive pill. 

Which of the following is the drug of choice?

Select the SINGLE most appropriate option from the list below. Select ONE option only.