14th July 2026

A 72-year-old male presents to clinic with a lesion on his back.

A 72-year-old male presents to clinic with a lesion on his back. He reports this lesion has increased in size but appears paler than it was a few months ago. The lesion is 10mm in diameter, has an irregular border and is variably pigmented with a central crust.  A superficial spreading melanoma was confirmed on histopathology.

What feature would be associated with a poor prognosis?

Which one of the following options is most likely to be associated with a poor prognosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.