27th August 2023

A 30-year-old female is involved in a severe car accident

A 30-year-old female is involved in a severe car accident. She is taken to the hospital with multiple fractures and internal injuries. She becomes hypotensive and tachycardic and develops difficulty breathing. Arterial blood gases show hypoxemia, and her chest X-ray shows bilateral infiltrates. She is intubated and mechanically ventilated. She also becomes oliguric, and her serum creatinine is elevated.

Which organ system is likely to fail next in the progression of MODS?