25th August 2023

A 30-year-old man presents to A&E with a widespread itchy rash

A 30-year-old man presents to A&E with a widespread itchy rash, difficulty breathing, and swelling of the lips and tongue. He had been eating a meal in a restaurant before the symptoms started. On examination, you note diffuse urticaria and swollen lips and tongue. His vitals show a heart rate of 115 bpm, blood pressure of 85/50 mmHg, respiratory rate of 24 breaths per minute, and oxygen saturation of 90% on room air.

What is the most appropriate immediate management?