27th August 2023

A 60-year-old female with a history of diabetes and hypertension is admitted to the ICU with severe pneumonia and septic shock

A 60-year-old female with a history of diabetes and hypertension is admitted to the ICU with severe pneumonia and septic shock. She is mechanically ventilated, and vasopressors are initiated. On day 2, she develops an acute kidney injury. Her blood cultures are positive for Streptococcus pneumoniae.

What is the most appropriate antibiotic choice?