26th April 2024

A 13-year-old girl is brought to the clinic by her parents who are concerned about her lack of breast development and absence of menstruation.

A 13-year-old girl is brought to the clinic by her parents who are concerned about her lack of breast development and absence of menstruation. She is otherwise healthy but is notably shorter than her peers. Her mother mentions that she started menstruating at the age of 14. Physical examination reveals a lack of secondary sexual characteristics, a prepubertal appearance, and a height below the 5th percentile for her age.

Which is the most likely diagnosis?