26th May 2025

A 21-year-old female presents to the Rheumatology outpatient department after being referred by her GP.

A 21-year-old female presents to the Rheumatology outpatient department after being referred by her GP. She complains of joint pains, swollen and puffy hands. On occasion, she notices that her fingers become very pale and painful in cold weather. On examination, she does not have any rashes or any joint deformities. Her sister also attends the Rheumatology clinic for an autoimmune illness, and she is concerned she may also have this condition. 

Which one of the following is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.