26th April 2024

A 25-year-old woman presents with a 10-day history of intermittent high fevers, chills, sweating, headaches, and general malaise.

A 25-year-old woman presents with a 10-day history of intermittent high fevers, chills, sweating, headaches, and general malaise. She recently returned from a month-long trip to sub-Saharan Africa.

On examination, her temperature is 39.3°C, pulse rate 102 bpm regular, and BP 110/60 mmHg. She appears fatigued and has mild pallor. No rash or lymphadenopathy is noted. A basic blood test reveals mild anaemia and thrombocytopenia.

Which one of the following is the most likely diagnosis?