22nd May 2025

A 28-year-old man with no past medical history presents with a first presentation of ulcerative colitis.

A 28-year-old man with no past medical history presents with a first presentation of ulcerative colitis. After 4 days, he continues to have diarrhoea. The stool chart shows 12 episodes of bloody diarrhoea today and 14 yesterday. He is on IV steroids. He was pyrexial this morning. He has had a sustained tachycardia of 110 bpm all day today. His CRP is 81 mg/litre (120 on admission). His platelets are 689 × 109/L and albumin is 27 g/litre. What is the most appropriate course of action?

Select the SINGLE most appropriate option from the list below. Select ONE option only.