28th May 2025

A 28-year-old woman is referred to gastroenterology outpatients after presenting to her GP with a one-year history of intermittent generalised abdominal pain associated with bloating and fluctuations in bowel habit.

A 28-year-old woman is referred to gastroenterology outpatients after presenting to her GP with a one-year history of intermittent generalised abdominal pain associated with bloating and fluctuations in bowel habit. She is otherwise well with no past medical history, no regular medications and no medication allergies. Clinical examination is unremarkable. Her GP performs some blood tests which reveal a normal full blood count, renal function, liver function and inflammatory markers. Her anti-tTGA and anti-EMA IgA antibodies are normal, and her total IgA level is low. Her faecal calprotectin level is normal.

What is the most appropriate next investigation for this woman?

Select the SINGLE most appropriate option from the list below. Select ONE option only.