30th April 2024

A 30-year-old woman presents with a 10-day history of fatigue, loss of appetite, and nausea.

A 30-year-old woman presents with a 10-day history of fatigue, loss of appetite, and nausea. She reports dark urine and has noticed a yellowish tint to her skin and eyes.. On examination, her temperature is 37.2°C, and she exhibits jaundice. There is mild tenderness in her right upper abdominal quadrant, but no hepatomegaly.

Investigations:

Temperature: 37.2°C

Pulse Rate: 80 bpm

Blood Pressure: 120/80 mmHg

Physical Examination: Mild right upper quadrant tenderness, jaundice

Which is the most appropriate diagnostic investigation?