30th April 2024

A 48-year-old woman presents with irregular menstrual cycles, hot flashes, and night sweats for the past six months.

A 48-year-old woman presents with irregular menstrual cycles, hot flashes, and night sweats for the past six months. She reports her menstrual cycles have been shorter and more unpredictable. She is sexually active and does not use contraception. She denies any vaginal bleeding after intercourse or between periods. Her last Pap smear was normal.

Which is the most appropriate diagnostic investigation to evaluate for menopause in this patient?