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30th April 2024
A 50-year-old man presents with fatigue, joint pain, and abdominal discomfort.
A 50-year-old man presents with fatigue, joint pain, and abdominal discomfort. He reports a family history of liver disease and diabetes. On examination, there is mild hepatomegaly but no skin pigmentation or other abnormalities.
Investigations:
Serum transferrin saturation: 55%
Serum ferritin: 750 picomols/L (normal: <300 nanograms/mL for men)
Liver function tests: Mildly elevated ALT and AST
Fasting blood sugar: Elevated
Which additional investigation is most likely to help with the diagnosis?
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