2nd May 2024

A 50-year-old woman, with a family history of breast cancer in her mother, presents with a recently noticed lump in her left breast.

A 50-year-old woman, with a family history of breast cancer in her mother, presents with a recently noticed lump in her left breast. She is postmenopausal and has no significant past medical history. On examination, a 2 cm firm, non-tender lump is palpable in the upper outer quadrant of her left breast. Mammography confirms the presence of a suspicious lesion.

Which is the most appropriate initial management?