3rd May 2024

A 55-year-old man presents with severe upper abdominal pain radiating to his back, nausea, and vomiting.

A 55-year-old man presents with severe upper abdominal pain radiating to his back, nausea, and vomiting. He has a history of heavy alcohol use. His vital signs are: blood pressure 100/70 mmHg, pulse 110 bpm, respiratory rate 24 breaths/min, and temperature 38.3°C. Physical examination reveals abdominal tenderness and guarding. Laboratory tests show elevated serum amylase and lipase. He is diagnosed with acute pancreatitis.

Which of the following is the most appropriate initial management step for this patient?