30th April 2024

A 58-year-old woman presents with a 4-month history of progressive dysphagia, particularly to solid foods, and recent onset of postprandial vomiting.

A 58-year-old woman presents with a 4-month history of progressive dysphagia, particularly to solid foods, and recent onset of postprandial vomiting. She reports unintentional weight loss of 8 kg over the last 3 months and occasional epigastric pain. She has a history of gastroesophageal reflux disease but is otherwise healthy. On examination, she appears malnourished and mildly dehydrated.

Investigations:

Vital signs: Normal temperature, pulse, and blood pressure.

Which investigation is most appropriate to confirm diagnosis?