29th April 2024

A 60-year-old man presents with a one-year history of progressive weakness in his arms and difficulty speaking.

A 60-year-old man presents with a one-year history of progressive weakness in his arms and difficulty speaking. Initially, he noticed difficulty lifting objects and now struggles with buttoning his shirt. His speech has become slurred and he occasionally chokes on food. On examination, there is atrophy of the hand muscles and fasciculations in the arms. His jaw jerk is brisk, and tongue fasciculation is noted. There is no sensory deficit.

Which is the most likely diagnosis?