2nd May 2024

A 65-year-old woman presents with a 6-month history of weight loss, anorexia, and epigastric pain.

A 65-year-old woman presents with a 6-month history of weight loss, anorexia, and epigastric pain. Upper gastrointestinal endoscopy reveals a 4 cm ulcerated lesion in the antrum of the stomach. Biopsy confirms adenocarcinoma. CT scan shows the tumour is localised to the stomach with no evidence of metastasis. The patient’s performance status is good, and she has no other significant comorbidities.

Which is the most appropriate management for this patient?