6th May 2024

A 68-year-old woman presents with a persistent cough and weight loss over the past 3 months.

A 68-year-old woman presents with a persistent cough and weight loss over the past 3 months. She has a 40 pack-year smoking history and quit smoking 10 years ago. A chest CT scan reveals a 3 cm mass in the right upper lobe and no evidence of distant metastases. Biopsy confirms non-small cell lung cancer (NSCLC), stage IIA. She has no significant comorbidities and is otherwise fit.

Which is the most appropriate initial management for this patient?