Torsade de pointes
This is a polymorphic VT which occurs with a prolonged QT interval (measured from start of Q wave to end of T wave). A long QT may be a result of a congenital genetic abnormality or acquired (see Table 3). Management includes stopping the precipitating agent which may resolve the episode of torsade. IV Magnesium is administered to stabilise the cardiac membrane and where there is haemodynamic instability DCCV is used.
| Medication | Class Ia and III antiarrhythmics e.g. sotalol, amiodarone.
Macrolide antibiotics Tricyclic antidepressants/antipsychotics e.g amitriptyline, imipramine, quetiapine, olanzapine. Antihistamines e.g. Loratadine |
| Electrolytes | Low potassium, magnesium or calcium |
| Temperature | Hypothermia |
| Congenital | Long QT syndrome – classified according to underlying genetic defect |
Table 3: Causes of QT prolongation. [Adapted from the Oxford Textbook of Medicine].
Take your subscriptions with you
Our mobile app allows you to access your interview and exam question banks wherever you are.