2nd February 2024

Pathophysiology

CNS sensitisation plays a central role such that the brain amplifies signals from peripheries and by modifying cortical processing > They feel more pain than expected (hyperalgesia), or they might feel pain without a stimulus present (allodynia)> Fear of pain > They avoid activities > The physical activities are deconditioned > lead to complete rest which is the reasonable behaviour but maladaptive that can be reinforced by friends and family