20th July 2023

Signs and Symptoms

Onset is usually in the 30s-/40s, and initial symptoms tend to be mood change or cognitive impairment. As the disease progresses, ataxia and poor gait follow.

It is classed as juvenile if onset is in the 20s – the predominant symptoms initially tend to be hypokinesia, then behavioural changes, including poor attention span, contractures, tremors, frequent falls, and seizures.

Table 3: Symptoms of Huntington’s Disease