Definition and prevalence | Medibuddy
11th April 2024

Definition and prevalence

Female sexual dysfunction includes a spectrum of disorders that are often multi-factorial in nature: sexual interest and arousal disorder (SIAD), female orgasmic disorder (FOD) and genito-pelvic penetration pain disorder (GPPPD), which includes dyspareunia and vaginismus. The exact prevalence of female sexual dysfunction is uncertain, as most studies have historically focused on male sexual dysfunction, but it is estimated to be between 11% overall and 41% in premenopausal women. There are 3 criteria for diagnosing a sexual disorder: (1) symptoms present for at least 6 months; (2) symptoms are experienced in ≥75% of sexual encounters; (3) symptoms have caused significant distress.

The aetiology of sexual dysfunction is often multifactorial and involves psychological, contextual, pharmacological and physiological factors. For instance, SIAD is strongly linked to mood disorders, such as depression and anxiety, in addition to PTSD and previous experience of abuse. GPPPD can be predominantly psychological in origin (as in vaginismus) but can also be due to surgical, medical and pharmacological causes (see Table 3).

Drug-Related SSRIs Aromatase inhibitors (letrozole, anastrozole)
Anti-hypertensives (β blockers, spironolactone, thiazides) Lithium
Anti-psychotics Opioids
Anti-epileptics
Medical Diabetes mellitus Perimenopause/menopause
Hyperthyroidism Pelvic inflammatory disorder (PID)
Hyperprolactinaemia STI
IBS/IBD Thyroid disorders
Interstitial cystitis UTI
Neurological disease (MS, Parkinson’s)
Surgical Adenomyosis Interstitial cystitis
Endometriosis Malignancy (endometrial, cervical)
FGM Ovarian cyst
Fibroids Previous pelvic surgery

Table 3. Non-psychological causes of female sexual dysfunction.

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