19th July 2023

A 17-year-old girl presents to a gastroenterology outpatient clinic with a 6-month history of abdominal pain

A 17-year-old girl presents to a gastroenterology outpatient clinic with a 6-month history of abdominal pain, bloating and occasional diarrhoea. Her blood tests reveal mildly elevated anti-tTGA (<10x the ULN). Therefore, she undergoes an upper GI endoscopy which confirms a diagnosis of coeliac disease.

What histological findings would most likely be present on her duodenal biopsies?

Select the SINGLE most appropriate option from the list below. Select ONE option only.