15th February 2024

A 2-year-old boy was born healthy. At eight months old, he began to have episodes of infections

A 2-year-old boy was born healthy. At eight months old, he began to have episodes of infections, including otitis media, pneumonia, sinusitis and deep-seated infections. His lymph nodes were impalpable on examination, and his tonsils were challenging to visualise. Blood tests showed undetectable immunoglobulin levels with near-undetectable levels of B-cell lymphocytes.

What is the underlying diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.