16th February 2024

A 23-year-old male presents to the immunology clinic with multiple episodes of sinusitis

A 23-year-old male presents to the immunology clinic with multiple episodes of sinusitis and pneumonia. Recent CT scans have revealed bronchiectasis. Alpha-1 antitrypsin levels were normal with normal CTFR gene tests. Immunoglobulin tests showed normal white cell counts with normal levels of B-cells and T-cells. Immunoglobulin levels showed raised IgM levels and reduced IgG, IgA and IgE levels.

What is the likely underlying diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.