4th March 2024

A 24-year-old female presents to the rheumatology clinic with widespread joint pains

A 24-year-old female presents to the rheumatology clinic with widespread joint pains. These joint pains are worst around her shoulders and knees, and the pain is described as a constant dull ache. She reports multiple episodes of shoulder and jaw dislocations as a child. She was able to reduce these dislocations by herself. Her skin easily bruises, tears on minimal injury and requires prolonged healing time. On examination today, multiple scars are visible on her shins and forearm with a “cigarette-paper” appearance. Skin hyperelasticity and multiple bruises along her hands and legs are also noted. She can touch her ᶠᶦᶠᵗʰ finger and thumb to her forearm, and her elbows can extend up to 15 degrees bilaterally.

Which of the following proteins is responsible for the underlying diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.