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7th April 2024
A 24-year-old lady with a background of dysmenorrhoea presents with hair loss and weight loss
A 24-year-old lady with a background of dysmenorrhoea presents with hair loss and weight loss despite having a good appetite. On examination, a fine tremor is noted in her outstretched hands. The remainder of the physical examination is unremarkable. Her GP requests some blood tests, which are shown below.
| Hb | 120g/L | Female (115-160g/L) |
| WBC | 9.0 x 10⁹/L | (4.0-11.0 x 10⁹/L) |
| Platelets | 200 x 10⁹/L | (150-500 x 10⁹/L) |
| MCV | 90fL | (82-100fL) |
| Corrected Calcium | 2.54 mmol/L | (2.1-2.6 mmol/L) |
| Vitamin B12 | 300 ng/L | (200-900 ng/L) |
| Folate | 5.0 nmol/L | (>3.0 nmol/L) |
| TSH | 0.1 mu/L | (0.5-5.5 mu/L) |
| Free T4 | 35 pmol/L | (9.0-22.0pmol/L) |
A diagnosis of hyperthyroidism is made and treatment options are discussed with the patient. How do thyroid hormones mediate their physiological actions?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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