28th February 2024

A 24-year-old male presents to the genetics clinic for his routine follow-up

A 24-year-old male presents to the genetics clinic for his routine follow-up. He plans to have a family with his wife and would like to know the risks of his children inheriting his genetic condition. His partner remains well, with no significant past medical history. The patient had a renal transplant due to end-stage renal failure at 18, and he recalls having episodes of haematuria during childhood. He also uses hearing aids due to sensorineural hearing loss. Both his maternal grandfather and mother have had renal transplants and hearing issues.

Given the likely diagnosis, what are the chances of his children developing this condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.