5th February 2024

A 24-year-old presents with fatigue, malaise and night sweats. Blood tests reveal a significantly raised WCC

A 24-year-old presents with fatigue, malaise and night sweats. Blood tests reveal a significantly raised WCC and LDH. Imaging shows widespread lymphadenopathy. A biopsy of one of the affected lymph nodes shows Reed-Sternberg cells. He was commenced on chemotherapy and subsequently developed acute haematuria approximately 24 hours after treatment commenced.

Given the likely cause of his haematuria, what is the mode of action of the underlying causative agent?

Select the SINGLE most appropriate option from the list below. Select ONE option only.