A 25-year-old male presents to the endocrine clinic due to treatment-resistant hypertension | Medibuddy
4th March 2024

A 25-year-old male presents to the endocrine clinic due to treatment-resistant hypertension

A 25-year-old male presents to the endocrine clinic due to treatment-resistant hypertension. He has remained well with no headaches, palpitations, sweats or chest pain symptoms. He had felt fatigued for the past 6-8 months but felt this was a result of returning to university. He recalls that his father and grandmother both had issues with hypertension since their early adulthood.

The examination was unremarkable. Blood tests were as follows:

Test Value Normal range
Na+ 136 135–145 mmol/L
K+ 2.8 3.5-5.5 mmol/L
Ur 6.4 2.5 – 7.8 mmol/L
Cr 90 60-100μmol/L
HCO3- 42 22-28 mmol/L

Renin and aldosterone levels were below the reference range.

What is the likely underlying diagnosis?

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