A 25-year-old male presents to the endocrine clinic due to treatment-resistant hypertension
A 25-year-old male presents to the endocrine clinic due to treatment-resistant hypertension. He has remained well with no headaches, palpitations, sweats or chest pain symptoms. He had felt fatigued for the past 6-8 months but felt this was a result of returning to university. He recalls that his father and grandmother both had issues with hypertension since their early adulthood.
The examination was unremarkable. Blood tests were as follows:
| Test | Value | Normal range |
|---|---|---|
| Na+ | 136 | 135–145 mmol/L |
| K+ | 2.8 | 3.5-5.5 mmol/L |
| Ur | 6.4 | 2.5 – 7.8 mmol/L |
| Cr | 90 | 60-100μmol/L |
| HCO3- | 42 | 22-28 mmol/L |
Renin and aldosterone levels were below the reference range.
What is the likely underlying diagnosis?
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