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22nd June 2023
A 26-year-old lady has commenced day 1 of R-CODOX-M chemotherapy for stage IV Burkitt’s lymphoma.
A 26-year-old lady has commenced day 1 of R-CODOX-M chemotherapy for stage IV Burkitt’s lymphoma. That afternoon, she became tachycardic and anuric.
The following biochemistry is demonstrated:
| Na⁺ | 135 mmol/L | (133-146 mmol/L) |
| K⁺ | 7.1 mmol/L | (3.5-5.3 mmol/L) |
| Urea | 25.2 mmol/L | (2.5-7.8 mmol/L) |
| Creatinine | 182 µmol/L | (80-115 µmol/L) |
| PO₄³⁻ | 2.7 mmol/L | (0.97-1.45 mmol/L) |
| Corrected Ca²⁺ | 1.5 mmol/L | (2.20-2.60 mmol/L) |
| Uric acid | 705 µmol/L | (140-360 µmol/L) |
| LDH | 1560 U/L | (<250 U/L) |
What is the next step in managing this patient?
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