20th March 2024

A 26-year-old male is seen in the emergency department by the medical team

A 26-year-old male is seen in the emergency department by the medical team. They are being treated for presumed cellulitis with IV flucloxacillin. After the infusion started the patient developed stridor, angioedema and had a blood pressure of 72/42 mmHg. They were given 500 micrograms of IM adrenaline, IV fluids and antihistamines. To confirm anaphylaxis, mast cell tryptase levels were taken by the on-call cardiac arrest team during initial management. A second sample was taken 2 hours after the patient’s deterioration. When should a third mast cell tryptase level be taken?

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