4th March 2024

A 30-year-old gentleman presents to the acute medical unit with jaundice

A 30-year-old gentleman presents to the acute medical unit with jaundice. He has been commenced on doxycycline due to concurrent bacterial pneumonia. He denies any abdominal pains. He recalls about three similar episodes occurring throughout his adolescence.

Physical examination was unremarkable apart from scleral icterus. Blood tests reveal an isolated mild hyperbilirubinemia at 60μmol/L with normal liver function tests. Further tests reveal his conjugated bilirubin levels are normal with raised unconjugated bilirubin.

What is the likely underlying cause for his jaundice?

Select the SINGLE most appropriate option from the list below. Select ONE option only.