3rd August 2023

A 31-year-old British traveller presents to A&E with fever, lethargy, and slightly yellow sclera.

A 31-year-old British traveller presents to A&E with fever, lethargy, and slightly yellow sclera. She returned 6 days ago from a 2-month backpacking trip through Cambodia and Laos. She took atovaquone-proguanil as malaria prophylaxis for 3 weeks but stopped this when she felt dizzy and nauseous. You perform a positive malaria rapid diagnostic test for Plasmodium falciparum species. Thick and Thin blood film shows malaria parasitaemia at 3.1%.

What is the most appropriate next step?

Select the SINGLE most appropriate option from the list below. Select ONE option only.