1st June 2023

A 32-year-old woman is seen in the Haematology Clinic by her obstetrician

A 32-year-old woman is seen in the Haematology Clinic by her obstetrician. She has suffered from four miscarriages over the last few years and has failed to have a successful pregnancy. Blood tests performed by the obstetrician, including a clotting screen, revealed a prolonged APTT.

You suspect antiphospholipid syndrome and have requested further blood tests, which reveal the presence of lupus anticoagulant on more than 2 occasions, at least 12 months apart.

Your patient informs you that she would still like to get pregnant. What treatment is recommended during pregnancy for this patient?