29th February 2024

A 34-year-old female has been admitted with right-sided weakness and facial droop

A 34-year-old female has been admitted with right-sided weakness and facial droop. An MRI scan showed an acute stroke within the left MCA territory with old infarcts within the left occipital and right temporal region. Given the history, blood lactate was checked. It was measured at 2.4mmol/L (normal: 0.5-1mmol/L). She also had developed hearing impairment over the past six years and had seizures over the past two years that are managed with antiepileptics.

Given the clinical diagnosis, what are the chances that her children develop the condition assuming 100% penetrance of the condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.