26th June 2023

A 35-year-old lady has presented to A&E with fever, shortness of breath, haemoptysis, and haematuria.

A 35-year-old lady has presented to A&E with fever, shortness of breath, haemoptysis, and haematuria. Her U&Es come back as follows:
Creatinine 253 μmol/L (normal range 60-120 μmol/L)
Urea 23 mmol/L (normal range 2.5-6.5 mmol/L)
Potassium 4.5 mmol/L (normal range 3.5-5.3 mmol/L).

CXR: Patchy hilar consolidation

ESR is normal and anti-glomerular basement membrane antibodies are positive.

What is the most likely cause of her acute renal failure?

Select the SINGLE most appropriate option from the list below. Select ONE option only.