5th January 2024

A 35-year-old patient was admitted to hospital with acute exacerbation of asthma

A 35-year-old patient was admitted to hospital with acute exacerbation of asthma. There was no other past medical history of note. The patient usually inhaled Salbutamol as required, Seretide inhaler twice daily, Montelukast and had recently been prescribed aminophylline 450 mg twice daily. The patient was started on nebulised bronchodilators, prednisolone and erythromycin as she is allergic to Penicillin. 72 hours later, she developed generalised tonic-clonic seizures. What was the most likely cause of the seizures?

Select the SINGLE most appropriate option from the list below. Select ONE option only.