1st August 2023

A 36-year-old woman with HIV presents to A&E with a three day history of abdominal pain and diarrhoea.

A 36-year-old woman with HIV presents to A&E with a three day history of abdominal pain and diarrhoea. She is febrile on assessment and has no recent travel history outside of the UK. Her most recent CD4 count is less than 50, and she says she has not been compliant with treatment for HIV. A colonoscopy, serology and positive antigen testing confirm the diagnosis.

What is the characteristic histological finding associated with this condition from colonoscopy?

Select the SINGLE most appropriate option from the list below. Select ONE option only.